Cyclopentyl 2-amino-4-methylpentanoate → Cyclopentyl 2-[3-[4-[2-amino-3-(4-fluoro-3-methylbenzoyl)-6-oxo-1-pyridinyl]-3,5-difluorophenoxy]propylamino]-4-methylpentanoate

HRID 698116Notes

Reaction equation

HRID 698116 reaction equation
[CH:36]1([O:41][C:42]([CH:43]([NH2:44])[CH2:45][CH:46]([CH3:47])[CH3:48])=[O:49])[CH2:37][CH2:38][CH2:39][CH2:40]1.[NH2:1][c:2]1[c:3]([C:26]([c:27]2[cH:28][c:29]([CH3:34])[c:30]([F:33])[cH:31][cH:32]2)=[O:35])[cH:4][cH:5][c:6](=[O:25])[n:7]1-[c:8]1[c:9]([F:24])[cH:10][c:11]([O:12][CH2:13][CH2:14][CH2:15][O:16][S:17]([CH3:18])(=[O:19])=[O:20])[cH:21][c:22]1[F:23]>>[NH2:1][c:2]1[c:3]([C:26]([c:27]2[cH:28][c:29]([CH3:34])[c:30]([F:33])[cH:31][cH:32]2)=[O:35])[cH:4][cH:5][c:6](=[O:25])[n:7]1-[c:8]1[c:9]([F:24])[cH:10][c:11]([O:12][CH2:13][CH2:14][CH2:15][NH:44][CH:43]([C:42]([O:41][CH:36]2[CH2:37][CH2:38][CH2:39][CH2:40]2)=[O:49])[CH2:45][CH:46]([CH3:47])[CH3:48])[cH:21][c:22]1[F:23]

Participants

3

Reactant 2

HCID 22671103Cyclopentyl 2-amino-4-methylpentanoateHCID 57658377Methanesulfonic acid 3-{4-[6-amino-5-(4-fluoro-3-methyl-benzoyl)-2-oxo-2H-pyridin-1-yl]-3,5-difluorophenoxy}propyl ester

Product 1

HCID 67447678Cyclopentyl 2-[3-[4-[2-amino-3-(4-fluoro-3-methylbenzoyl)-6-oxo-1-pyridinyl]-3,5-difluorophenoxy]propylamino]-4-methylpentanoate

Sources & evidence

ORD record
ord-e11dd0ceef1f4f3d8203fbd4cad401ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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