3-bromo-2-tert-butyl-1-(4-fluoro-phenyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester → 2-tert-Butyl-1-(4-fluoro-phenyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([O:2][C:3]([c:4]1[c:5]([OH:6])[c:7]2[cH:8][c:9](-[c:10]3[cH:11][cH:12][c:13]([F:14])[cH:15][cH:16]3)[n:17](-[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:24]2[cH:25][n:26]1)=[O:27])[CH3:28].[CH2:29]([CH3:30])[O:31][C:32](=[O:33])[c:34]1[c:35]([OH:55])[c:36]2[c:37]([cH:38][n:39]1)[n:40](-[c:48]1[cH:49][cH:50][c:51]([F:54])[cH:52][cH:53]1)[c:41]([C:44]([CH3:45])([CH3:46])[CH3:47])[c:42]2[Br:43]>>[CH2:29]([CH3:30])[O:31][C:32](=[O:33])[c:34]1[c:35]([OH:55])[c:36]2[c:37]([cH:38][n:39]1)[n:40](-[c:48]1[cH:49][cH:50][c:51]([F:54])[cH:52][cH:53]1)[c:41]([C:44]([CH3:45])([CH3:46])[CH3:47])[cH:42]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7df0dee09d394e99b87877b781f5bf70
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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