HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanediamine, N1,N1,N2-trimethyl- → N1,N1,N2-trimethyl-N2-(3-nitropyridin-4-yl)ethane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanediamine, N1,N1,N2-trimethyl- | HCID 67338 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N1,N1,N2-trimethyl-N2-(3-nitropyridin-4-yl)ethane-1,2-diamine | HCID 68184585 | — |
Reaction Steps
The method of Example 1 was followed using 4-chloro-3-nitropyridine (1.0 eq), N1,N1,N2-trimethyl ethane-1,2-diamine (2.0 eq), and DIEA (2.0 eq) in EtOH yielding N1,N1,N2-trimethyl-N2-(3-nitropyridin-4-yl)ethane-1,2-diamine which was concentrated and taken on as is. LCMS (m/z): 225.1 (MH+); LC Rt=0.574 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822497B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-5810ff7c773e447ab8ad2707a945e607 |
| Source note | uspto-grants-2014_09 |