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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 698387Generated: October 29, 2026

Dimethylformamide → 2-[3',5'-Dichloro-4'-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-4-yloxy]-2-methyl-propionic acid ethyl ester

https://huagongshe.com/reaction/698387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPropanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 11745—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
Reactant1-Cyclohexyl-3-(3,5-dichloro-4'-hydroxy-biphenyl-4-ylmethyl)-pyrrolidin-2-oneHCID 59299335—
Product2-[3',5'-Dichloro-4'-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-biphenyl-4-yloxy]-2-methyl-propionic acid ethyl esterHCID 11606223—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-57d26420d92f46dcbca57189dd0315cb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)