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HRID69839

反应详情

EQUATION

反应方程式

HRID 69839 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccc(F)cc1F
HCID67967

1-Nitro-2,4-difluorobenzene

C6H3F2NO2

结构：CC(C)(C)OC(=O)NC1CCNCC1
HCID723833

4-(N-Boc-amino)piperidine

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2cc(F)ccc2[N+](=O)[O-])CC1
HCID69044868

未命名化合物

收率 93%

PROCEDURE

实验过程

Method 1 was followed using 1 eq each of 1,3-difluoro-4-nitrobenzene, 4-(N-Boc-amino) piperidine, and TEA yielding tert-butyl 1-(5-fluoro-2-nitrophenyl)-piperidin-4-ylcarbamate (93%). LCMS (m/z): 340.1 (MH+); LC Rt=3.24 min.