Dichloromethane → (2-{4-[3-(3-Trifluoromethyl-phenyl)-ureido]-imidazol-1-yl}ethyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][n:10]1[cH:11][n:12][c:13]([NH2:15])[cH:14]1)=[O:16].[Cl:30][CH2:31][Cl:32].[F:17][C:18]([c:19]1[cH:20][c:21]([N:25]=[C:26]=[O:27])[cH:22][cH:23][cH:24]1)([F:28])[F:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][n:10]1[cH:11][n:12][c:13]([NH:15][C:26]([NH:25][c:21]2[cH:20][c:19]([C:18]([F:17])([F:28])[F:29])[cH:24][cH:23][cH:22]2)=[O:27])[cH:14]1)=[O:16]Participants
4
Sources & evidence
- ORD record
- ord-b6231a76bbbb47d9886212978cdd061f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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