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HRID69860

反应详情

EQUATION

反应方程式

HRID 69860 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1
HCID313137

1-Fluoro-4-(methanesulfonyl)-2-nitrobenzene

C7H6FNO4S

结构：CC(C)(C)OC(=O)NC1CCNCC1
HCID723833

4-(N-Boc-amino)piperidine

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(S(C)(=O)=O)cc2[N+](=O)[O-])CC1
HCID69046390

未命名化合物

PROCEDURE

实验过程

Method 1 was followed using 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq), 4-(N-Boc-amino) piperidine (1.1 eq), and TEA (2.0 eq) at 55° C. for 24 hours yielding tert-butyl 1-(4-(methylsulfonyl)-2-nitrophenyl)piperidin-4-ylcarbamate. LCMS (m/z): 400.1 (MH+); LC Rt=2.83 min.

WORKUP

后处理

  1. customat 55° C.
  2. customfor 24 hours