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HRID69867

反应详情

EQUATION

反应方程式

HRID 69867 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2[N+](=O)[O-])CC1
HCID53426214

tert-Butyl 4-[2-nitro-4-(trifluoromethyl)phenyl]piperazine-1-carboxylate

C16H20F3N3O4

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2N)CC1
HCID53426177

tert-Butyl 4-[2-amino-4-(trifluoromethyl)phenyl]piperazine-1-carboxylate

C16H22F3N3O2

收率 99%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Following the method of Example 49 (Method 2), tert-butyl 4-(2-nitro-4-(trifluoro-methyl)phenyl)piperazine-1-carboxylate in MeOH was reduced yielding tert-butyl 4-(2-amino-4-(trifluoromethyl)phenyl)piperazine-1-carboxylate (99%). LCMS (m/z): 346.1 (MH+); LC Rt=3.38 min.