1,2-Ethanediamine, N1,N1,N2-trimethyl- → 4-[(5,7-Difluoro-3,4-dihydro-2H-chromen-4-yl)oxy]-N-[2-(dimethylamino)ethyl]-N,2-dimethyl-1H-benzimidazole-6-carboxamide

HRID 698674Notes

Reaction equation

HRID 698674 reaction equation
[CH3:27][N:28]([CH2:29][CH2:30][NH:31][CH3:32])[CH3:33].[F:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([F:12])[cH:11]1)[O:7][CH2:6][CH2:5][CH:4]2[O:13][c:14]1[cH:15][c:16]([C:24](=[O:25])[OH:26])[cH:17][c:18]2[nH:19][c:20]([CH3:23])[n:21][c:22]12>>[F:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([F:12])[cH:11]1)[O:7][CH2:6][CH2:5][CH:4]2[O:13][c:14]1[cH:15][c:16]([C:24](=[O:26])[N:31]([CH2:30][CH2:29][N:28]([CH3:27])[CH3:33])[CH3:32])[cH:17][c:18]2[nH:19][c:20]([CH3:23])[n:21][c:22]12

Participants

3

Reactant 2

HCID 673381,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 685745597-[(5,7-Difluorochroman-4-yl)oxy]-2-methyl-1H-benzo[d]imidazole-5-carboxylic Acid

Product 1

HCID 589001974-[(5,7-Difluoro-3,4-dihydro-2H-chromen-4-yl)oxy]-N-[2-(dimethylamino)ethyl]-N,2-dimethyl-1H-benzimidazole-6-carboxamide

Sources & evidence

ORD record
ord-b9f6430c9c264bf3ba3dde88deb058cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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