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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 698679Generated: October 28, 2026

Hydrochloric Acid → 1-{3-Fluoro-4-[(phenylmethyl)oxy]phenyl}-4-hydroxy-1H-indole-6-carbonitrile

https://huagongshe.com/reaction/698679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantEthyl AcetateHCID 8857—
ReactantPalladiumHCID 23938—
Reactant1,4-DioxaneHCID 31275—
ReactantDibenzylidene acetoneHCID 95417—
ReactantDi-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphaneHCID 11618717—
Reactant4-bromo-1-{3-fluoro-4-[(phenylmethyl)oxy]phenyl}-1H-indole-6-carbonitrileHCID 67136097—
Product1-{3-Fluoro-4-[(phenylmethyl)oxy]phenyl}-4-hydroxy-1H-indole-6-carbonitrileHCID 66876793—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-b76f8758db4645e98dce9a5aac246c52
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)