Methanol → 3-[4-[1-Hydroxy-2-(2-fluorophenyl)ethyl]piperidino]methyl-1H-pyrazin-2-one
Reaction equation
[BH4-:25].[CH3:31][OH:32].[Cl:28][CH2:29][Cl:30].[F:1][c:2]1[c:3]([CH2:8][C:9](=[O:10])[CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[c:19](=[O:24])[nH:20][cH:21][cH:22][n:23]3)[CH2:15][CH2:16]2)[cH:4][cH:5][cH:6][cH:7]1.[Na+:26].[OH2:27]>>[F:1][c:2]1[c:3]([CH2:8][CH:9]([OH:10])[CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][c:18]3[c:19](=[O:24])[nH:20][cH:21][cH:22][n:23]3)[CH2:15][CH2:16]2)[cH:4][cH:5][cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-549518b782a44c5b896de3ca5d6aebba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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