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HRID69887

反应详情

EQUATION

反应方程式

HRID 69887 的结构方程式

REACTANTS

反应物

2
结构：Nc1nc(N)c(C(=O)O)nc1Cl
HCID6452119

3,5-Diamino-6-chloro-pyrazine acid

C5H5ClN4O2

结构：CC(C)(C)OC(=O)NC1CCCN(c2ccncc2N)C1
HCID67130164

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2NC(=O)c2nc(Cl)c(N)nc2N)C1
HCID86669186

未命名化合物

收率 57%

PROCEDURE

实验过程

Following method 11, tert-butyl 1-(3-aminopyridin-4-yl)piperidin-3-ylcarbamate was coupled to 3,5-diamino-6-chloropyrazine-2-carboxylic acid yielding (S)-tert-butyl 1-(3-(3,5-diamino-6-chloropyrazine-2-carboxamido)pyridin-4-yl)piperidin-3-ylcarbamate (57%). LCMS (m/z): 463.1 (MH+); LC Rt=2.36 min.