HRID69929

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID45480452

3-Amino-6-bromopyridine-2-carboxylic acid

C6H5BrN2O2

结构：CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2N)CC[C@H]1F

HCID58386807

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2NC(=O)c2nc(Br)ccc2N)CC[C@H]1F

HCID88862444

未命名化合物

PROCEDURE

实验过程

Following Method 11 of Example 305, trans-(+/−)-tert-butyl 1-(3-aminopyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate and 3-amino-6-bromopicolinic acid were reacted yielding after purification (+/−)-tert-butyl 1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate, (20%). LCMS (m/z): 510.9 (MH+).

WORKUP

后处理

customwere reacted
customyielding
customafter purification (+/−)-tert-butyl 1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-4-fluoropiperidin-3-ylcarbamate, (20%)