4-(1-Pyrrolidinyl)piperidine → [5-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

HRID 699368Notes

Reaction equation

HRID 699368 reaction equation
[CH:1]1([c:4]2[c:5]([C:26](=[O:27])[OH:28])[c:6](-[c:20]3[cH:21][cH:22][n:23][cH:24][cH:25]3)[n:7][n:8]2-[c:9]2[cH:10][c:11]([O:15][C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3]1.[N:29]1([CH:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[CH2:30][CH2:31][CH2:32][CH2:33]1>>[CH:1]1([c:4]2[c:5]([C:26](=[O:28])[N:37]3[CH2:36][CH2:35][CH:34]([N:29]4[CH2:30][CH2:31][CH2:32][CH2:33]4)[CH2:39][CH2:38]3)[c:6](-[c:20]3[cH:21][cH:22][n:23][cH:24][cH:25]3)[n:7][n:8]2-[c:9]2[cH:10][c:11]([O:15][C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 787034-(1-Pyrrolidinyl)piperidineHCID 673156045-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazole-4-carboxylic acid

Product 1

HCID 25206417[5-Cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethoxy-phenyl)-1H-pyrazol-4-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

Sources & evidence

ORD record
ord-9d4f8f28fe174ba5aca95ed78619699d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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