Dichloromethane → 4-bromo-2-methoxy-5-methyl-7-(trifluoroacetyl)-6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepin-3-amine
Reaction equation
[CH3:9][O:10][c:11]1[c:12]([NH2:29])[cH:13][c:14]2[c:15]([n:28]1)[CH2:16][CH2:17][N:18]([C:22]([C:23]([F:24])([F:25])[F:26])=[O:27])[CH2:19][CH:20]2[CH3:21].[Cl:30][CH2:31][Cl:32].[O:1]=[C:2]1[N:3]([Br:8])[C:4](=[O:5])[CH2:6][CH2:7]1>>[Br:8][c:13]1[c:12]([NH2:29])[c:11]([O:10][CH3:9])[n:28][c:15]2[c:14]1[CH:20]([CH3:21])[CH2:19][N:18]([C:22]([C:23]([F:24])([F:25])[F:26])=[O:27])[CH2:17][CH2:16]2Participants
4
Sources & evidence
- ORD record
- ord-2ebce06761894113a1da2e5c850716ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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