Water → 3-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propan-1-ol

HRID 699552Notes

Reaction equation

HRID 699552 reaction equation
[Br:17][CH2:18][CH2:19][CH2:20][OH:21].[CH3:22][C:23]#[N:24].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1.[OH2:25]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:18][CH2:19][CH2:20][OH:21])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1

Participants

5

Reactant 4

HCID 962WaterHCID 6342AcetonitrileHCID 123083-Bromo-1-propanolHCID 8494213-(4-Piperidyl)-6-fluoro-1,2-benzisoxazole

Product 1

HCID 153849663-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)propan-1-ol

Sources & evidence

ORD record
ord-7bf2e293ae8940a783fb6dd6a5d325b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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