Acetone → 5-(4-Bromo-butoxy)-1-(4-fluoro-phenyl)-1H-indole

HRID 699568Notes

Reaction equation

HRID 699568 reaction equation
[Br:24][CH2:25][CH2:26][CH2:27][CH2:28][Br:29].[CH3:30][C:31](=[O:32])[CH3:33].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([OH:17])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1.[K+:18].[K+:19].[O-:20][C:21]([O-:22])=[O:23]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([O:17][CH2:28][CH2:27][CH2:26][CH2:25][Br:24])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 80561,4-DibromobutaneHCID 19660Carbonate IonHCID 114815561-(4-Fluoro-phenyl)-1H-indol-5-ol

Product 1

HCID 186794275-(4-Bromo-butoxy)-1-(4-fluoro-phenyl)-1H-indole

Sources & evidence

ORD record
ord-102bd123b5df47a7b7b9d3d83baeae3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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