Methyl phenyl sulfone → 2-(3'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

HRID 699615Notes

Reaction equation

HRID 699615 reaction equation
[BH:1]([OH:2])[OH:3].[Br:14][c:15]1[cH:16][cH:17][c:18](-[c:21]2[o:22][c:23]([CH3:33])[c:24]([CH2:26][CH2:27][N:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[n:25]2)[cH:19][cH:20]1.[CH3:4][S:5](=[O:6])(=[O:7])[c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1>>[CH3:4][S:5](=[O:6])(=[O:7])[c:8]1[cH:9][cH:10][cH:11][c:12](-[c:15]2[cH:16][cH:17][c:18](-[c:21]3[o:22][c:23]([CH3:33])[c:24]([CH2:26][CH2:27][N:28]4[CH2:29][CH2:30][CH2:31][CH2:32]4)[n:25]3)[cH:19][cH:20]2)[cH:13]1

Participants

4

Reactant 3

HCID 18369Methyl phenyl sulfoneHCID 61668Boronic AcidHCID 116815462-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Product 1

HCID 115316572-(3'-Methanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Sources & evidence

ORD record
ord-6c8624ceac8b4f3bb770705e288b6982
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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