HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-6-bromopicolinic acid → HCID 86669213, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-6-bromopicolinic acid | HCID 45480452 | — |
| Reactant | tert-butyl (3S,5R)-1-(3-aminopyridin-4-yl)-5-(tert-butyldimethylsilyloxy)piperidin-3-ylcarbamate | HCID 68919475 | — |
| Product | HCID 86669213 | HCID 86669213 | — |
Reaction Steps
Following Method 11 of Example 305, tert-butyl (3S,5R)-1-(3-aminopyridin-4-yl)-5-(tert-butyldimethylsilyloxy)piperidin-3-ylcarbamate and 6-bromo-3-aminopicolinic acid were coupled to yield tert-butyl (3S,5R)-1-(3-(3-amino-6-bromopicolinamido)pyridin-4-yl)-5-(tert-butyldimethylsilyloxy)piperidin-3-ylcarbamate. LCMS (m/z): 621.1/623.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822497B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d07ef3f0eaea497fbd69b7ff8ab42622 |
| Source note | uspto-grants-2014_09 |