Methanol → 3-(3-(4-(4-Fluoro-benzyloxy)-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine
Reaction equation
[CH3:32][OH:33].[F:23][c:24]1[cH:25][cH:26][c:27]([CH2:28][Br:29])[cH:30][cH:31]1.[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]2)[n:11][o:12]1.[Na+:22].[OH-:21]>>[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH2:28][c:27]3[cH:26][cH:25][c:24]([F:23])[cH:31][cH:30]3)[cH:18][cH:19]2)[n:11][o:12]1Participants
6
Sources & evidence
- ORD record
- ord-be696c450e024a07b6b22bf8f282494a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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