Ammonium → 2-(tetrahydro-2H-pyran-4-yloxy)pyridin-3-amine

HRID 699996Notes

Reaction equation

HRID 699996 reaction equation
[CH3:24][OH:25].[CH:17]([O-:18])=[O:19].[CH:21]([OH:22])=[O:23].[N+:1]([O-:2])(=[O:3])[c:4]1[c:5]([O:10][CH:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[n:6][cH:7][cH:8][cH:9]1.[NH4+:20].[OH-:26].[OH-:28].[Pd+2:27]>>[NH2:1][c:4]1[c:5]([O:10][CH:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[n:6][cH:7][cH:8][cH:9]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 283FormateHCID 284Formic AcidHCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 532567153-Nitro-2-(tetrahydro-2H-pyran-4-yloxy)pyridine

Product 1

HCID 532566082-(tetrahydro-2H-pyran-4-yloxy)pyridin-3-amine

Sources & evidence

ORD record
ord-ae1ad471b96047869aed7ccab2809844
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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