Citric Acid → 1,5-Bis-benzyloxy-naphthalene-2-carboxylic acid

Participants

Reaction Steps

1,5-Bis-benzyloxy-naphthalene-2-carboxylic acid benzyl ester (0.556 g, 1.17 mmol), MeOH (6.4 mL) and NaOH (1.25 mL), H2O (65.0 mL) and citric acid (0.28 g, 1.5 mmol) Yield: 0.507 g creamy white solid (92% yield). 1H NMR (400 MHz CDCl3) δ 5.23 (s, 2H), δ 5.28 (s, 2H), δ 7.06 (d, J=7.3 Hz, 1H), δ 7.38-7.55 (m, 11H), δ 7.83 (d, J=8.7 Hz, 1H), δ 8.08 (d, J=8.7 Hz, 1H), δ 8.26 (d, J=8.7 Hz, 1H).

Provenance & Evidence