N'-[4-(4-bromo-1-ethyl-1H-pyrazol-3-yl)phenyl]-N,N-dimethylurea → N'-(4-{1-ethyl-4-[2-[4-(4-morpholinyl)phenyl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea

HRID 700145Notes

Reaction equation

HRID 700145 reaction equation
[Br:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([S:23](=[O:24])(=[O:25])[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[c:9](-[c:11]1[cH:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[cH:15][cH:16]1)[cH:10]2.[Br:32][c:33]1[c:34](-[c:40]2[cH:41][cH:42][c:43]([NH:46][C:47]([N:48]([CH3:49])[CH3:50])=[O:51])[cH:44][cH:45]2)[n:35][n:36]([CH2:38][CH3:39])[cH:37]1>>[c:2]1(-[c:33]2[c:34](-[c:40]3[cH:41][cH:42][c:43]([NH:46][C:47]([N:48]([CH3:49])[CH3:50])=[O:51])[cH:44][cH:45]3)[n:35][n:36]([CH2:38][CH3:39])[cH:37]2)[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([S:23](=[O:24])(=[O:25])[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[c:9](-[c:11]1[cH:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[cH:15][cH:16]1)[cH:10]2

Participants

3

Reactant 2

HCID 68999367N'-[4-(4-bromo-1-ethyl-1H-pyrazol-3-yl)phenyl]-N,N-dimethylureaHCID 69000477HCID 69000477, compound

Product 1

HCID 68997545N'-(4-{1-ethyl-4-[2-[4-(4-morpholinyl)phenyl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea

Sources & evidence

ORD record
ord-f06c0ca5bd2b4c689c10875153209a45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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