7-amino-2-methyl-4-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-2,3-dihydro-1H-isoindol-1-one → Fak-IN-16
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:30][c:31]1[cH:32][cH:33][c:34]([CH:42]2[CH2:43][CH2:44][CH:45]([N:48]3[CH2:49][CH2:50][N:51]([CH3:54])[CH2:52][CH2:53]3)[CH2:46][CH2:47]2)[c:35]2[c:39]1[C:38](=[O:40])[N:37]([CH3:41])[CH2:36]2>>[c:2]1([NH:30][c:31]2[cH:32][cH:33][c:34]([CH:42]3[CH2:43][CH2:44][CH:45]([N:48]4[CH2:49][CH2:50][N:51]([CH3:54])[CH2:52][CH2:53]4)[CH2:46][CH2:47]3)[c:35]3[c:39]2[C:38](=[O:40])[N:37]([CH3:41])[CH2:36]3)[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Sources & evidence
- ORD record
- ord-b134938fde3d4c37b615b935d9adcd4c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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