HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-(+)-Cysteine → (2-(1H-indol-2-yl)thiazol-4-yl)(1H-indol-5-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-(+)-Cysteine | HCID 5862 | — |
| Reactant | 4-(3,4,5-Trimethoxybenzoyl)-2-phenylthiazole | HCID 25227430 | — |
| Reactant | 2-(1H-indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid | HCID 57516834 | — |
| Product | (2-(1H-indol-2-yl)thiazol-4-yl)(1H-indol-5-yl)methanone | HCID 136047813 | — |
Reaction Steps
(2-(1H-indol-2-yl)thiazol-4-yl)(1H-indol-5-yl)methanone (21) was prepared using the similar method as used of compound 1h from 2-(1H-indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid and cysteine. 1H NMR (500 MHz, CDCl3) δ 9.60 (s, 1H), 9.26 (s, 1H), 8.31 (s, 1H), 8.03 (s, 1H), 7.83 (dd, 1H), 7.69 (d, 1H), 7.53-7.49 (m, 2H), 7.41 (t, 1H), 7.33 (t, 1H), 7.21-7.18 (m, 2H), 7.13 (s, 1H). MS (ESI) m/z 366.1 (M+Na)+, 341.9 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822513B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-ef9400d3894a442fb193c41fb139a7e4 |
| Source note | uspto-grants-2014_09 |