2-Propenoic acid, 3-(2-chloro-4-fluorophenyl)- → 3-(2-chloro-4-fluorophenyl)-N-[1-[[5-(1,1-difluoroethyl)furan-2-yl]methyl]pyrazol-3-yl]prop-2-enamide

HRID 700505Notes

Reaction equation

HRID 700505 reaction equation
[Cl:17][c:18]1[c:19]([CH:25]=[CH:26][C:27](=[O:28])[OH:29])[cH:20][cH:21][c:22]([F:24])[cH:23]1.[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH2:16])[cH:14][cH:15]2)[o:9]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][c:13]([NH:16][C:27]([CH:26]=[CH:25][c:19]3[c:18]([Cl:17])[cH:23][c:22]([F:24])[cH:21][cH:20]3)=[O:28])[cH:14][cH:15]2)[o:9]1

Participants

3

Reactant 2

HCID 27250652-Propenoic acid, 3-(2-chloro-4-fluorophenyl)-HCID 669293691-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine

Product 1

HCID 669287013-(2-chloro-4-fluorophenyl)-N-[1-[[5-(1,1-difluoroethyl)furan-2-yl]methyl]pyrazol-3-yl]prop-2-enamide

Sources & evidence

ORD record
ord-9c511f3d32e34e35a3c1911ef44709fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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