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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 700547Generated: October 26, 2026

N-methyl-2-pyrrolidone → N-(3-fluoro-4-pyridinyl)-6-((trans-4-hydroxycyclohexyl)amino)-8-(3-isoxazolylamino)imidazo[1,2-b]pyridazine-3-carboxamide

https://huagongshe.com/reaction/700547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant4-AminocyclohexanolHCID 81293—
Reactant6-chloro-N-(3-fluoropyridin-4-yl)-8-(isoxazol-3-ylamino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624780—
ProductN-(3-fluoro-4-pyridinyl)-6-((trans-4-hydroxycyclohexyl)amino)-8-(3-isoxazolylamino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624826—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-d4a00f4f886344788a9752b7e15e04ef
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)