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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 700817Generated: October 26, 2026

Tetrahydrofuran → (+/-)-4-Oxo-2-pyrimidin-4-yl-4,6,7,8,9,10-hexahydro-pyrimido[1,2-a]azepine-10-carboxylic acid (4-nitro-phenyl) ester

https://huagongshe.com/reaction/700817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant4-Nitrophenyl chloroformateHCID 82129—
ReactantNpc316347HCID 3280088—
Reactant2-pyrimidin-4-yl-7,8,9,10-tetrahydro-6H-pyrimido[1,2-a]azepin-4-oneHCID 67177629—
Product(+/-)-4-Oxo-2-pyrimidin-4-yl-4,6,7,8,9,10-hexahydro-pyrimido[1,2-a]azepine-10-carboxylic acid (4-nitro-phenyl) esterHCID 67178000—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-ff9b7257adb742639f59bfadea519c6b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)