1-Methyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine → 1-(2,5-Difluorobenzyl)-7-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine
Reaction equation
[CH3:21][N:22]1[CH2:23][CH2:24][N:25]([c:28]2[n:29][cH:30][c:31]([B:34]3[O:35][C:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[O:42]3)[cH:32][cH:33]2)[CH2:26][CH2:27]1.[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13]([I:15])[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:16][c:17]([F:20])[cH:18][cH:19]1>>[F:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13](-[c:31]4[cH:30][n:29][c:28]([N:25]5[CH2:24][CH2:23][N:22]([CH3:21])[CH2:27][CH2:26]5)[cH:33][cH:32]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[cH:16][c:17]([F:20])[cH:18][cH:19]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-66bb1ee079844e7689bdbbd7e53c7834
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…