Methanol → N1-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-5-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-(2-hydroxyphenyl)malonamide
Reaction equation
[B:39]([Br:40])([Br:41])[Br:42].[CH3:46][OH:47].[Cl:43][CH2:44][Cl:45].[F:1][c:2]1[cH:3][c:4]([NH:24][C:25]([CH2:26][C:27](=[O:28])[NH:29][c:30]2[c:31]([O:36][CH3:37])[cH:32][cH:33][cH:34][cH:35]2)=[O:38])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[cH:19][n:20][cH:21][n:22]1[CH3:23])[s:17]2.[OH2:48]>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:25]([CH2:26][C:27](=[O:28])[NH:29][c:30]2[c:31]([OH:36])[cH:32][cH:33][cH:34][cH:35]2)=[O:38])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[cH:19][n:20][cH:21][n:22]1[CH3:23])[s:17]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e523139545cf49aeaa415a25574f55e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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