5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-Amino-1-(4,4-difluorocyclohexyl)-1h-pyrazole-4-carboxamide
Reaction equation
[NH2:18][c:19]1[c:20]([C:32]#[N:33])[cH:21][n:22][n:23]1[CH:24]1[CH2:25][CH2:26][C:27]([F:30])([F:31])[CH2:28][CH2:29]1.[NH2:1][c:2]1[n:3](-[c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[O:13][CH3:10])[n:11][cH:12][c:14]1[C:15]([NH2:16])=[O:17]>>[O:13]=[C:32]([c:20]1[c:19]([NH2:18])[n:23]([CH:24]2[CH2:25][CH2:26][C:27]([F:30])([F:31])[CH2:28][CH2:29]2)[n:22][cH:21]1)[NH2:33]Participants
3
Sources & evidence
- ORD record
- ord-a74cb6248adb4b8ca1af62682d191d86
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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