tert-Butyl piperazine-1-carboxylate → Ethyl 3-methyl-2-[4-(tert-butoxycarbonyl)piperazin-1-yl]isonicotinate

HRID 701248Notes

Reaction equation

HRID 701248 reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[N:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[Cl:1][c:2]1[c:3]([CH3:13])[c:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[cH:10][cH:11][n:12]1>>[c:2]1([N:24]2[CH2:23][CH2:22][N:21]([C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:26][CH2:25]2)[c:3]([CH3:13])[c:4]([C:5](=[O:6])[O:7][CH2:8][CH3:9])[cH:10][cH:11][n:12]1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 2762478Ethyl 2-chloro-3-methylisonicotinate

Product 1

HCID 22180458Ethyl 3-methyl-2-[4-(tert-butoxycarbonyl)piperazin-1-yl]isonicotinate

Sources & evidence

ORD record
ord-582be9ea401a4e2382e210346142de1d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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