4-(4-tert-butoxycarbonyl-1-piperazinyl)methyl-6-(3-fluoro-4-methoxyphenyl)-2-[3-(4-fluorophenyl)propyl]-2H-pyridazin-3-one → 4-aminomethyl-6-(3-fluoro-4-methoxyphenyl)-2-[3-(4-fluorophenyl)propyl]-2H-pyridazin-3-one
Reaction equation
[C:1]([O:2][C:3]([N:4]1[CH2:5][CH2:6][N:11]([CH2:14][c:15]2[c:16](=[O:40])[n:17]([CH2:30][CH2:31][CH2:32][c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:18][c:19](-[c:21]3[cH:22][c:23]([F:29])[c:24]([O:27][CH3:28])[cH:25][cH:26]3)[cH:20]2)[CH2:7][CH2:8]1)=[O:9])([CH3:10])([CH3:12])[CH3:13].[F:41][c:42]1[cH:43][c:44](-[c:45]2[cH:46][c:47]([CH2:48][O:49][S:50]([CH3:51])(=[O:52])=[O:53])[c:54](=[O:55])[n:56]([CH2:57][CH2:58][CH2:59][c:60]3[cH:61][cH:62][c:63]([F:64])[cH:65][cH:66]3)[n:67]2)[cH:68][cH:69][c:70]1[O:71][CH3:72]>>[NH2:11][CH2:14][c:15]1[c:16](=[O:40])[n:17]([CH2:30][CH2:31][CH2:32][c:33]2[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]2)[n:18][c:19](-[c:21]2[cH:22][c:23]([F:29])[c:24]([O:27][CH3:28])[cH:25][cH:26]2)[cH:20]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-cfbed5adcc634e25a56376cbd5051617
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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