Methanol → Tert-butyl 4-[2-[4-(5,6-dichloro-1-oxo-3,4-dihydroisoquinolin-2-yl)phenyl]ethyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

HRID 701820Notes

Reaction equation

HRID 701820 reaction equation
[CH3:38][OH:39].[Cl:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][c:11]1[Cl:12])[C:7](=[O:13])[N:6]([c:14]1[cH:15][cH:16][c:17]([CH:18]=[CH:19][CH:20]3[N:21]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[C:22]([CH3:25])([CH3:26])[O:23][CH2:24]3)[cH:34][cH:35]1)[CH2:5][CH2:4]2.[H:36][H:37]>>[Cl:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][c:11]1[Cl:12])[C:7](=[O:13])[N:6]([c:14]1[cH:15][cH:16][c:17]([CH2:18][CH2:19][CH:20]3[N:21]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[C:22]([CH3:25])([CH3:26])[O:23][CH2:24]3)[cH:34][cH:35]1)[CH2:5][CH2:4]2

Participants

4

Reactant 3

HCID 887MethanolHCID 67151849HCID 67151849, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 67151678Tert-butyl 4-[2-[4-(5,6-dichloro-1-oxo-3,4-dihydroisoquinolin-2-yl)phenyl]ethyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Sources & evidence

ORD record
ord-8f62ae5c68d844a5b2efbc2b5c39c073
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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