Potassium Cation → 6-[2-[4-[(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]ethyl]-2,3-dihydro-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
Reaction equation
[Br:1][CH2:2][CH2:3][c:4]1[c:5]([CH3:14])[n:6][c:7]2[n:8]([c:9]1=[O:10])[CH2:11][CH2:12][S:13]2.[CH3:38][CH:39]([CH3:40])[CH2:41][C:42](=[O:43])[CH3:44].[F:15][c:16]1[cH:17][cH:18][c:19]([CH:22]([OH:23])[CH:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[cH:20][cH:21]1.[I-:37].[K+:36].[Na+:30].[Na+:31].[O-:32][C:33](=[O:34])[O-:35]>>[CH2:2]([CH2:3][c:4]1[c:5]([CH3:14])[n:6][c:7]2[n:8]([c:9]1=[O:10])[CH2:11][CH2:12][S:13]2)[N:27]1[CH2:26][CH2:25][CH:24]([CH:22]([c:19]2[cH:18][cH:17][c:16]([F:15])[cH:21][cH:20]2)[OH:23])[CH2:29][CH2:28]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-49970137f3e640828333fe640caf2544
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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