3-Isopropoxybenzoyl chloride → 2-[3-(4-Trifluoromethyl-phenyl)-1-(3-isopropoxy-benzoyl)-pyrrolidin-3-yl]-ethanol
Reaction equation
[CH:19]([CH3:20])([CH3:21])[O:22][c:23]1[cH:24][c:25]([C:26](=[O:27])[Cl:28])[cH:29][cH:30][cH:31]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:17])[F:18]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][N:11]([C:26]([c:25]3[cH:24][c:23]([O:22][CH:19]([CH3:20])[CH3:21])[cH:31][cH:30][cH:29]3)=[O:27])[CH2:12][CH2:13]2)[cH:7][cH:8]1)([F:17])[F:18]Participants
3
Sources & evidence
- ORD record
- ord-7c1230a009404a038572456c7798a9ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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