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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 702361Generated: November 1, 2026

piperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylate → 4-[7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinolin-2(1h)-yl]-2-cyclopropyl-2-methyl-4-oxobutanenitrile

https://huagongshe.com/reaction/702361

Reaction equation

Participants

RoleNameHCIDCharge
Reactantpiperidin-4-yl 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinoline-2(1H)-carboxylateHCID 59496558—
Reactant3-Cyano-3-cyclopropylbutanoic acidHCID 59496710—
Product4-[7-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-3,4-dihydroisoquinolin-2(1h)-yl]-2-cyclopropyl-2-methyl-4-oxobutanenitrileHCID 59496619—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-2ecb31d223f64b69a0ad1bfeac5a9e8b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)