Methyl iodide → O1-tert-butyl O2-methyl 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate

HRID 702437Notes

Reaction equation

HRID 702437 reaction equation
[C:19]([c:20]1[cH:21][c:22]([CH3:23])[cH:24][c:25]([C:26]([CH3:27])([CH3:28])[CH3:29])[n:30]1)([CH3:31])([CH3:32])[CH3:33].[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:7][CH:8]([CH2:10][OH:11])[CH2:9]1.[Cl:36][CH2:37][Cl:38].[I:34][CH3:35]>>[CH3:1][O:2][C:3](=[O:4])[CH:5]1[N:6]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:7][CH:8]([CH2:10][O:11][CH3:19])[CH2:9]1

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 6344DichloromethaneHCID 988982,6-Di-tert-butyl-4-methylpyridineHCID 235957531-(tert-Butyl) 2-methyl 4-(hydroxymethyl)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 66621318O1-tert-butyl O2-methyl 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-264ea9a776514a31917b14cdfe5736d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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