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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 702439Generated: October 29, 2026

Toluene → 5-(5-Chloropyridin-3-ylethynyl)-2-fluorobenzamide

https://huagongshe.com/reaction/702439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant3-Chloro-5-ethynylpyridineHCID 23500887—
Reactant2-Fluoro-5-iodobenzamideHCID 67047811—
Product5-(5-Chloropyridin-3-ylethynyl)-2-fluorobenzamideHCID 67047706—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-fe221b71968c41a9a13f1ef96edb56f5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)