Acetic Acid → 3-(5-Amino-2-chloro-phenoxymethyl)-azetidine-1-carboxylic Acid Tert-Butyl Ester

HRID 703005Notes

Reaction equation

HRID 703005 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][O:13][c:14]2[c:15]([Cl:23])[cH:16][cH:17][c:18]([N+:20]([O-:21])=[O:22])[cH:19]2)[CH2:11]1.[CH3:24][OH:25].[CH3:27][C:28](=[O:29])[OH:30].[OH2:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:12][O:13][c:14]2[c:15]([Cl:23])[cH:16][cH:17][c:18]([NH2:20])[cH:19]2)[CH2:11]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 887MethanolHCID 962WaterHCID 685324463-(2-Chloro-5-nitro-phenoxymethyl)-azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 689129313-(5-Amino-2-chloro-phenoxymethyl)-azetidine-1-carboxylic Acid Tert-Butyl Ester

Sources & evidence

ORD record
ord-b01745f8ff1c4131b11bb4907fb79e6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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