HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Chloro-2,4,5-trifluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,4,5-Trifluorobenzoic acid | HCID 521170 | — |
| Reactant | 3-Chloro-2,4,5-trifluorobenzoic Acid | HCID 2734269 | — |
| Product | 3-Chloro-2,4,5-trifluorobenzoyl chloride | HCID 2782245 | — |
Reaction Steps
Chlorination of 2,4,5-trifluorobenzoic acid in chlorosulphonic acid leads to 3-chloro-2,4,5-trifluorobenzoic acid, which is reacted as the crude product with thionyl chloride to give 3-chloro-2,4,5-trifluorobenzoyl chloride (boiling point 94°/18 mbar; nD20 =1.5164): ##STR15##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04981854 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-c0734b5703f94849aad48417adbc702e |
| Source note | uspto-grants-1991_01 |