2,6-Di-tert-butyl-4-mercaptophenol → HCID 15056308, compound

HRID 703108Notes

Reaction equation

HRID 703108 reaction equation
[CH3:1][C:2]([C:5]1[CH:10]=[C:9]([SH:11])[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:4])[CH3:3].[O:17]=[C:18]([N:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1)[CH:19]=[CH:20][CH3:21]>CO>[CH3:4][C:2]([C:5]1[CH:10]=[C:9]([S:11][CH:20]([CH3:21])[CH2:19][C:18]([N:22]2[CH2:26][CH2:25][CH2:24][CH2:23]2)=[O:17])[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:1])[CH3:3]

Participants

4

Reactant 2

HCID 703702,6-Di-tert-butyl-4-mercaptophenolHCID 142892HCID 142892, compound

Product 1

HCID 15056308HCID 15056308, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Following the procedure of Example 4, 2,6-bis(1,1-dimethylethyl)4-mercaptophenol (2.0 g. 0.008 mole) and 1(1-oxo-2-butenyl)pyrrolidine (1.11 g, 0.008 mole) were dissolved in methanol (20 ml) under an argon atmosphere and refluxed for 24 hours. The solvent was removed and the product isolated by chromatography on silica, and recrystallized from hexane to yield the product as a white solid, m.p. about 95°-99° C.

Workup

  1. temperaturerefluxed for 24 hours
  2. customThe solvent was removed
  3. customthe product isolated by chromatography on silica
  4. customrecrystallized from hexane

Sources & evidence

ORD record
ord-b10a6f06578a4f53a0f2f978e7cbc084
Source dataset
uspto-grants-1991_01
Patent number
US04981853

Reaction notes

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