HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetic Acid → 2-(2-Oxopyrrolidin-1-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | HCID 20061776 | HCID 20061776 | — |
| Product | 2-(2-Oxopyrrolidin-1-yl)acetic acid | HCID 3146687 | — |
Reaction Steps
--[(2-oxazolin-2-yl)methyl]-2-pyrrolidone, for example, can be obtained by condensation of pyrrolidone and chloroacetic acid to form 2-pyrrolidone acetic acid, where m =I in the above formula (II), or, alternatively, by condensing butyrolactone with glycine, and the starting carboxylic acid condensed with ethanolamine and cyclodehydrated to form 1-[(2-oxazolin-2-yl)methyl]-2-pyrrolidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04981974 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-551682c1e7e947748650d5652139db93 |
| Source note | uspto-grants-1991_01 |