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HRID70328

反应详情

EQUATION

反应方程式

HRID 70328 的结构方程式

REACTANTS

反应物

2
结构：NC(=O)c1cccc(B(O)O)c1
HCID2737814

3-Aminocarbonylphenylboronic acid

C7H8BNO3

结构：N#Cc1ccc(I)c(C(F)(F)F)c1
HCID22625194

4-Iodo-3-(trifluoromethyl)benzonitrile

C8H3F3IN

PRODUCTS

生成物

1
结构：N#Cc1ccc(-c2cccc(C(N)=O)c2)c(C(F)(F)F)c1
HCID67160792

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
催化剂HCID178418397

未命名化合物

结构：CCO.Cc1ccccc1
溶剂HCID21863594

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized from 3-(aminocarbonyl)phenyl boronic acid and 4-iodo-3-(trifluoromethyl)benzonitrile (I-IX-6) according to the procedure described for Ex IX-10, using Pd(PPh3)4 catalyst and PhMe/EtOH (4:1) as organic cosolvents. LC/MS (method A) 2.18 min, m/z 291 (M+H).

WORKUP

后处理

  1. customLC/MS (method A) 2.18 min, m/z 291 (M+H)