反应详情

A mixture of 13.6 g of 4-[(2-hexyl-4-tetradecylphenoxy)methyl]-2,2-dimethyl-1,3-dioxolane, 10 ml of 5% hydrochloric acid and 250 ml of tetrahydrofuran was heated at reflux for 4 hours, then allowed to cool and the tetrahydrofuran removed under reduced pressure. The mixture was then extracted several times with ethyl acetate. The organic extracts were combined, washed with aqueous sodium bicarbonate, dried and the solvent evaporated, giving 12.3 g of the desired compound.

1. temperaturewas heated
2. temperatureat reflux for 4 hours
3. temperatureto cool
4. customthe tetrahydrofuran removed under reduced pressure
5. extractionThe mixture was then extracted several times with ethyl acetate
6. washwashed with aqueous sodium bicarbonate
7. customdried
8. customthe solvent evaporated