Benzaldehyde → HCID 178513837, compound

Participants

Reaction Steps

In 0.7 ml of acetic acid, 245 mg (0.6 mmol) of oxamide 4-chloro-3-[(2,2,-3,3,4,4,4-heptafluorobutoxy)methyl]phenylhydrazone was dissolved and nitrogen was saturated. The solution was added with 76 mg (0.72 mmol) of benzaldehyde under a nitrogen atmosphere and stirred at room temperature for 16 hours. Then water was added to the solution and the formed crystals were filtered out, washed with water and dried in vacuo. The resulting product was recrystallized from ethyl acetate/n-hexane with nitrogen saturated to obtain 257 mg (86.5% yield) of 1-[4-chloro-3-](2,2,3,3,4,4,4-heptafluorobutoxy)methyl]phenyl]-4,5-dihydro-5-phenyl-1H-1,2,4-triazole-3-carboxamide (m.p. 157°-159° C.).

Provenance & Evidence