Diazomethane → HCID 15916889, compound

Participants

Reaction Steps

To a solution of 450 mg (1.52 mmoles) of (S)-7-benzyloxycarbonylamino -3-hydroxyheptanoic acid in 1,2-dimethoxyethane, while being cooled in ice, was added dropwise 7 ml (4.56 mmoles) of a solution of diazomethane in ether. The mixture was stirred for 30 minutes. The reaction mixture was evaporated to dryness to yield 461 mg (98% yield) of (S)-7-benzyloxycarbonylamino-3-hydroxyheptanoic acid methyl ester;[α]D21 +1°.

Provenance & Evidence