HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenylacetic Acid → HCID 131716750, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenylacetic Acid | HCID 7690 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | HCID 67940826 | HCID 67940826 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131716750 | HCID 131716750 | — |
Reaction Steps
To (±)-cis-3-ethyl-4-hydroxymethyl-N-toluenesulfonyl-2-azetidinone (3.3 mg) and p-methoxyphenylacetic acid (3.7 mg) in CH2Cl2 (0.6 ml) was added dicyclohexylcarbodiimide (DCC) (5 mg) followed by p-dimethylaminopyridine (DMAP) (1 mg). The mixture was stirred overnight, at room temperature and then purified via preparative tlc on a silica gel plate and developed with CH2Cl2 to yield the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04983597 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-83e557014090403ca8dc43edc701801f |
| Source note | uspto-grants-1991_01 |