3,5-Dichlorophenyl isocyanate → HCID 15616373, compound

HRID 703409Notes

Reaction equation

HRID 703409 reaction equation
[NH2:1][CH:2]1[CH2:6][N:5]([CH2:7][CH3:8])[N:4]([CH2:9][CH3:10])[CH2:3]1.[Cl:11][C:12]1[CH:13]=[C:14]([N:19]=[C:20]=[O:21])[CH:15]=[C:16]([Cl:18])[CH:17]=1>C1(C)C=CC=CC=1>[Cl:11][C:12]1[CH:13]=[C:14]([NH:19][C:20]([NH:1][CH:2]2[CH2:6][N:5]([CH2:7][CH3:8])[N:4]([CH2:9][CH3:10])[CH2:3]2)=[O:21])[CH:15]=[C:16]([Cl:18])[CH:17]=1

Participants

4

Reactant 2

HCID 944603,5-Dichlorophenyl isocyanateHCID 5591991,2-Diethyl-4-pyrazolidinamine

Product 1

HCID 15616373HCID 15616373, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

A solution of 4-amino-1,2-diethylpyrazolidine (1.26 g, 8.8 mmol) in anhydrous toluene (5 ml) was added to a solution of 3,5-dichlorophenyl isocyanate (1.71 g, 9.1 mmol) in dry toluene (20 ml) and the mixture stirred overnight. The precipitated solid was collected, washed with toluene and dried to give the title compound, 1.94 g. This was converted to the 1:1 maleate, mp 165°-167° C.

Workup

  1. customThe precipitated solid was collected
  2. washwashed with toluene
  3. customdried

Sources & evidence

ORD record
ord-7992b663e8b84a3d8efe197d7ad29a80
Source dataset
uspto-grants-1991_01
Patent number
US04983600

Reaction notes

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