4-Chlorophenyl Isocyanate → HCID 15616379, compound

HRID 703411Notes

Reaction equation

HRID 703411 reaction equation
[NH2:1][CH:2]1[CH:7]2[CH2:8][CH2:9][N:4]([CH2:5][CH2:6]2)[CH2:3]1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([N:17]=[C:18]=[O:19])=[CH:13][CH:12]=1>>[N:4]12[CH2:9][CH2:8][CH:7]([CH2:6][CH2:5]1)[CH:2]([NH:1][C:18]([NH:17][C:14]1[CH:15]=[CH:16][C:11]([Cl:10])=[CH:12][CH:13]=1)=[O:19])[CH2:3]2

Participants

3

Reactant 2

HCID 76934-Chlorophenyl IsocyanateHCID 1232383-Aminoquinuclidine

Product 1

HCID 15616379HCID 15616379, compound

Procedure

The above compound was prepared, following the procedure of Example 1, from 3-aminoquinuclidine (0.63 g, 5 mmol) and 4-chlorophenyl isocyanate (0.768 g, 5 mmol). The product was purified as the 1:1 maleate (1.23 g), mp 182°-183° C. (dec).

Workup

  1. customThe above compound was prepared
  2. customThe product was purified as the 1:1 maleate (1.23 g), mp 182°-183° C. (dec)

Sources & evidence

ORD record
ord-9b1907664ad8486ab4817c0918617d1e
Source dataset
uspto-grants-1991_01
Patent number
US04983600

Reaction notes

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